Ultimately, people are people. We all want to be happy. We want to be safe and comfortable. Silly people make us laugh and assholes make us angry. All the minor differences between people are just that: minor. By and large, we're all the same, and the best policy is to treat people in the same way.
You may be surprised to find out how rarely this happens. After all, treating a woman the same way I treat a man was all it took to have game.